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Panama Canal cruises

Panama Canal One-Way via Cartagena, Panama Canal & Huatulco

Cartagena · Colón (Panama Canal) · Panama Canal · Huatulco (Santa María Huatulco) · Cabo San Lucas · San Diego · Los Angeles

Balanced route with a steady mix of port days and sea days. Covers Colombia, Panama, Mexico, and United States. Includes scenic-cruising segments.

18 nights Miami Panama Canal 8 ports 9 sea days
Compare departures Explore the route

What this trip feels like

Balanced, varied and easy to pace

This route gives you a steady mix of ship time and 8 ports. It suits travelers who want meaningful days ashore without turning every day into an early start and a tightly planned port call.

Balanced pace

8 ports in 18 nights

A steady alternation between time onboard and time ashore.

Broad destination variety

Cartagena · Colón (Panama Canal) · Huatulco (Santa María Huatulco) + more

Frequent changes of scenery across the itinerary.

Route logistics

Sails from Miami

Check the exact departure and arrival ports before arranging flights.

Port experience

Colón (Panama Canal) · Expect plenty of cruise traffic

This port regularly handles substantial cruise traffic, although conditions still vary by date.

Best for · A mix of ship and shore time · First-time visitors · Travelers who like a steady pace

Think twice if · You want either an all-ports itinerary or a mostly ship-focused escape

Best departures

Best upcoming sailings

Start here. These departures surface first because they combine stronger pricing, useful timing, or a notable warning signal for this itinerary.

Best overall value
MSC Cruises

MSC Poesia

Miami → Cartagena → Los Angeles → Seattle

Apr 8 · 18 nights

About average

$1,536 inside · $85/night

All departures

All upcoming departures

Compare all sailings for this itinerary.

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Itinerary pricing

What this itinerary usually costs

Typical pricing runs around $98/night, with most departures landing in the $93-$113/night band across 1 tracked sailing.

Typical price

$98/night

$1,757 total

Normal range

$93-$113/night

$1,673-$2,029 total

Lowest recent fare

$85/night

$1,536 total

Comparison set

1 sailings

Used for itinerary baseline

When should I go?

Not enough departures yet to identify a reliable cheaper season.

Route overview

How this route is built

Compare sailings →

18 nights · 8 port calls · 9 sea days · 4 countries

8 port calls across Colombia, Panama, Mexico, United States · Neither especially port-heavy nor sea-day heavy for this trip length.

  1. 1

    Embark in Miami

    Embarkation ports can vary by sailing

  2. 2

    Cartagena

    Colombia · Southern Caribbean

  3. 3

    Colón (Panama Canal)

    Panama · Panama Canal

  4. 4

    Panama Canal

    Panama · Panama Canal

    Scenic cruising
  5. 5

    Panama Canal

    Panama · Panama Canal

    Scenic cruising
  6. 6

    Huatulco (Santa María Huatulco)

    Mexico

  7. 7

    Cabo San Lucas

    Mexico · Mexican Riviera

  8. 8

    San Diego

    United States · West Coast

  9. 9

    Los Angeles

    United States · West Coast

  10. 10

    Disembark in Seattle

    Disembarkation ports can vary by sailing

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Embark port
Disembark port
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Other routes to consider

Not quite the right itinerary? Compare routes that trade a little simplicity for more ports, different destinations, or a longer trip.

FAQ

What’s the best month to sail this itinerary?
It depends on weather and crowd levels. Use the sailing list to compare dates and prioritize port days with comfortable conditions.
Are these sailings all the same route?
They can be close but not identical. Look for differences in port order, arrival times, and sea day placement.
How should I choose between two similar sailings?
Compare: (1) ship, (2) port day timing, (3) number of sea days, (4) price vs cabin value, and (5) flight convenience.