A mix of ports and sea days
For balancing time ashore with time on board.
Cartagena · Oranjestad · Willemstad
Explore this itinerary →
Mexico & Central America
Panama Canal Cruises
Routes here bring ports such as Panama Canal, Colón (Panama Canal), and Panama City into reach. Choose how much time you want ashore versus on the ship, then compare departure ports and dates.
Popular trip length: 7 nights
Private destination options
Start with the route
Choose your kind of trip
A few different ways to explore Panama Canal, drawn from itineraries with upcoming departures.
Start and finish somewhere different
For combining a cruise with stays in two different places.
Balboa · Panama Canal · Balboa · Puerto Jimenez + 1 more
Explore this itinerary →More days at sea
For travelers who want time to enjoy the ship between stops.
Ocho Rios · Cartagena · Colón (Panama Canal) · Puerto Limón + 8 more
Explore this itinerary →More time exploring ports
For travelers who want a route focused on destinations.
Quepos · Puerto Jimenez · Balboa · Panama Canal
Explore this itinerary →Current sailings worth comparing
Departures in Panama Canal whose cabin-level price history currently points to favorable pricing. Compare the fare and booking context on each sailing.
Plan your dates and budget
When to go & what it costs
- $2,629
- $1,652–$5,999
- $588
Compare departure months
October 2027 has the lowest median nightly fare in the months shown; December 2026 has the highest.
Nov 2026
$124
Dec 2026
$312
Jan 2027
$155
Feb 2027
$153
Mar 2027
$155
Apr 2027
$127
May 2027
$732
Sep 2027
$104
Oct 2027
$99
Nov 2027
$269
Dec 2027
$290
Jan 2028
$201
Alerts
Get deal alerts for Panama Canal
We'll email you when unusually cheap cruises appear in this region.
Where should I start?
Choose your departure port
Balance route choice and cruise fare with the cost of getting to the port.
Get to know Panama Canal
Loading map...
Key ports
The ports most central to cruising in Panama Canal.
Ships sailing this region
Ships with strong presence in Panama Canal.
Grandeur of the Seas
Royal Caribbean International
38 sailings
$873
Island Princess
Princess Cruises
24 sailings
$1,169
Viking Mars
Viking Cruises
21 sailings
$3,799
Le Bellot
Ponant Cruises
21 sailings
$5,539
More ships
Nieuw Amsterdam
Holland America
20 sailings
$1,099
Oosterdam
Holland America
17 sailings
$1,979
Star Pride
Windstar Cruises
16 sailings
$2,416
MSC Poesia
MSC Cruises
15 sailings
$588
Norwegian Sun
Norwegian Cruise Line
14 sailings
$769
Coral Princess
Princess Cruises
12 sailings
$1,849
Le Laperouse
Ponant Cruises
12 sailings
$5,539
Star Legend
Windstar Cruises
11 sailings
$2,878
Carnival Spirit
Carnival Cruise Line
9 sailings
$901
Wind Star
Windstar Cruises
8 sailings
$3,485
Emerald Azzurra
Emerald Cruises
8 sailings
$11,790
Queen Anne
Cunard Line
7 sailings
$2,537
Oceania Marina
Oceania Cruises
7 sailings
$3,149
Le Bougainville
Ponant Cruises
7 sailings
$5,377
Cruise lines in Panama Canal
Explore more itineraries
- ABC Islands Loop via Cartagena & Oranjestad
- Panama Canal One-Way: Balboa & Panama Canal
- Western Caribbean Arc: Montego Bay, Colón & Cozumel
- Panama Canal One-Way from Fort Lauderdale to Los Angeles: Oranjestad, Panama Canal & Puntarenas
- Panama Canal One-Way: Puerto Jimenez & Panama Canal
- Western Caribbean Loop via Cozumel & Puerto Limón
- ABC Islands Loop via Cartagena & Kralendijk
- Panama Canal One-Way: Half Moon Cay, Oranjestad & Panama Canal
- Panama Canal One-Way: Portobelo & Panama Canal
- Panama Canal Loop via Puerto Limón & Colón
- Panama Canal Repositioning from Los Angeles to Fort Lauderdale: Puerto Vallarta, Puerto Quetzal & Panama Canal
- Western Caribbean Loop: Ocho Rios, Cartagena & Colón
More upcoming Panama Canal cruises
Featured departures
More departures to explore
Upcoming departures with complete itinerary, availability, and current pricing data.
Norwegian Sun
Miami → Great Stirrup Cay → Georgetown, Grand Cayman → Miami
Nov 6, 2026 · 12 nights
$5,261 · $438/night
Celebrity Summit
Tampa → George Town, Great Exuma Island → Cartagena → Los Angeles
Apr 18, 2027 · 15 nights
$1,793 · $120/night
Carnival Miracle
Galveston → Cozumel → Roatán → Galveston
Dec 7, 2026 · 10 nights
$880 · $88/night
Grandeur of the Seas
Cartagena → Kralendijk → Colón (Panama Canal) → Cartagena
Mar 14, 2027 · 7 nights
$1,234 · $176/night
About Panama Canal cruises
Panama Canal has 291 itineraries, 404 upcoming sailings, and calls across 9 ports.
The most common cruise lengths in Panama Canal tend to be 7 nights, 10 nights, and 16 nights.
Based on currently tracked pricing, one of the more affordable departure periods appears to be October 2027.
Frequently asked questions
What kinds of cruises are available in Panama Canal?
Panama Canal currently has 291 itineraries and 404 upcoming sailings.
How much do Panama Canal cruises cost?
The median future sailing price in Panama Canal is about $2,629.
When is the cheapest time to cruise Panama Canal?
October 2027 appears to be one of the more affordable departure periods.