Panama Canal cruises

Panama Canal One-Way via Cabo San Lucas, Puerto Quetzal & Panama Canal (Rare Variant)

⚓ Cabo San Lucas · Acapulco · Puerto Quetzal · Puerto Caldera · Panamá, Ciudad de · Panama Canal · Cartagena · Falmouth · Miami

Balanced route with a steady mix of port days and sea days. Covers Mexico, Guatemala, Costa Rica, and Panama and more. Includes scenic-cruising segments.

☾16–19 nights Los Angeles Panama Canal 9 ports 7 sea days

Itinerary pricing

What this itinerary usually costs

Typical pricing runs around $111/night. with most departures landing in the $80-$123/night band. across 2 tracked sailings.

Typical price

$111/night

$2,113 total

Normal range

$80-$123/night

$1,529-$2,331 total

Lowest recent fare

Building history

$1,099 total

Comparison set

2 sailings

Used for itinerary baseline

Best departures

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When should I go?

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October 2026
Cheapest
Median price/night
$87
2 sailings
Upcoming departures
Typical value
2 priced departures tracked

Route overview

How this route is built

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16–19 nights · 9 port calls · 7 sea days · 7 countries

9 port calls across Mexico, Guatemala, Costa Rica, Panama · Neither especially port-heavy nor sea-day heavy for this trip length.

  1. 1

    Embark in Los Angeles

    Embarkation ports can vary by sailing

  2. 2

    Cabo San Lucas

    Mexico · Mexican Riviera

  3. 3

    Acapulco

    Mexico · Mexican Riviera

  4. 4

    Puerto Quetzal

    Guatemala · Central America

  5. 5

    Puerto Caldera

    Costa Rica · Central America

  6. 6

    Panamá, Ciudad de

    Panama · Panama Canal

  7. 7

    Panama Canal

    Panama · Panama Canal

    Scenic cruising
  8. 8

    Cartagena

    Colombia · Southern Caribbean

  9. 9

    Falmouth

    Jamaica · Western Caribbean

  10. 10

    Miami

    United States · US East Coast

  11. 11

    Disembark in Miami or New York

    Disembarkation ports can vary by sailing

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Embark port
Disembark port
Port of call

Alternatives

Compare nearby alternatives

Nearby options in the same planning set, with price and trip-shape tradeoffs called out so you can compare without restarting your search.

FAQ

What’s the best month to sail this itinerary?

It depends on weather and crowd levels. Use the sailing list to compare dates and prioritize port days with comfortable conditions.

Are these sailings all the same route?

They can be close but not identical. Look for differences in port order, arrival times, and sea day placement.

How should I choose between two similar sailings?

Compare: (1) ship, (2) port day timing, (3) number of sea days, (4) price vs cabin value, and (5) flight convenience.