Transatlantic cruises

Transatlantic Crossing: Salerno, Valletta & Panama Canal

Salerno · Messina · Valletta · La Goulette Nord (Halqueloued) · Cagliari · Alicante · Cartagena · Melilla · Málaga · Cadiz · Lisboa · Portimao · Funchal, Madeira · Santa Cruz de Tenerife · Santa Cruz de La Palma · San Juan · Miami · Georgetown, Grand Cayman · Cartagena · Panama Canal · Puntarenas · Corinto · Puerto Quetzal · Acapulco · Puerto Vallarta

Extended 45-night voyage with 19 sea days and 25 ports. Covers Italy, Malta, Tunisia, Spain, and more. Includes scenic-cruising segments.

45 nights Civitavecchia (Rome) Transatlantic 25 ports 19 sea days

What this trip feels like

Expansive, immersive and built around life at sea

At 45 nights, this is a multi-month, world-cruise-style voyage rather than a conventional getaway. 19 sea days make the ship your home base between 25 ports across a wide arc of destinations. Expect long ocean passages and the planning commitment of an extended journey.

Long-form pace

25 ports in 45 nights

Long ocean passages make onboard routines a major part of the experience.

Broad destination variety

Salerno · Messina · Valletta + more

Frequent changes of scenery across the itinerary.

Route logistics

Sails from Civitavecchia (Rome)

Check the exact departure and arrival ports before arranging flights.

Port experience

Salerno · Pick your date carefully

Cruise traffic varies substantially by date, so your specific port day can feel very different depending on when you visit.

Best for · Long-form travelers · Sea-day lovers · Multi-region exploration

Think twice if · You want a conventional one- or two-week cruise

Best departures

Best upcoming sailings

Start here. These departures surface first because they combine stronger pricing, useful timing, or a notable warning signal for this itinerary.

All departures

All upcoming departures

Compare all sailings for this itinerary.

Itinerary pricing

What this itinerary usually costs

Typical pricing runs around $485/night, with most departures landing in the $433-$500/night band across 1 tracked sailing.

Typical price

$485/night

$21,804 total

Normal range

$433-$500/night

$19,472-$22,496 total

Lowest recent fare

$422/night

$18,999 total

Comparison set

1 sailings

Used for itinerary baseline

When should I go?

Not enough departures yet to identify a reliable cheaper season.

Route overview

How this route is built

Compare sailings →

45 nights · 25 port calls · 19 sea days · 14 countries

25 port calls across Italy, Malta, Tunisia, Spain · Neither especially port-heavy nor sea-day heavy for this trip length.

  1. 1

    Embark in Civitavecchia (Rome)

    Embarkation ports can vary by sailing

  2. 2

    Salerno

    Italy · Western Mediterranean

  3. 3

    Messina

    Italy · Western Mediterranean

  4. 4

    Valletta

    Malta · Western Mediterranean

  5. 5

    La Goulette Nord (Halqueloued)

    Tunisia · Western Mediterranean

  6. 6

    Cagliari

    Italy · Western Mediterranean

  7. 7

    Alicante

    Spain · Western Mediterranean

  8. 8

    Cartagena

    Spain · Western Mediterranean

  9. 9

    Melilla

    Spain · Western Mediterranean

  10. 10

    Málaga

    Spain · Western Mediterranean

  11. 11

    Cadiz

    Spain · Portugal & Spain Atlantic Coast

  12. 12

    Lisboa

    Portugal · Portugal & Spain Atlantic Coast

  13. 13

    Portimao

    Portugal · Portugal & Spain Atlantic Coast

  14. 14

    Funchal, Madeira

    Portugal · Madeira

  15. 15

    Santa Cruz de Tenerife

    Spain · Canary Islands

  16. 16

    Santa Cruz de La Palma

    Spain · Canary Islands

  17. 17

    San Juan

    Puerto Rico · Eastern Caribbean

  18. 18

    Miami

    United States · US East Coast

  19. 19

    Georgetown, Grand Cayman

    Cayman Islands · Western Caribbean

  20. 20

    Cartagena

    Colombia · Southern Caribbean

  21. 21

    Panama Canal

    Panama · Panama Canal

    Scenic cruising
  22. 22

    Puntarenas

    Costa Rica · Central America

  23. 23

    Corinto

    Nicaragua · Central America

  24. 24

    Puerto Quetzal

    Guatemala · Central America

  25. 25

    Acapulco

    Mexico · Mexican Riviera

  26. 26

    Puerto Vallarta

    Mexico · Mexican Riviera

  27. 27

    Disembark in Los Angeles

    Disembarkation ports can vary by sailing

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Embark port
Disembark port
Port of call

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