Long-form pace
21 ports in 36 nights
Long ocean passages mean substantial time aboard.
Patagonia & Cape Horn cruises
Patagonia & Cape Horn One-Way: Cabo San Lucas, Darwin Channel & Strait of Magellan
Cabo San Lucas · Huatulco (Santa María Huatulco) · Puerto Quetzal · Puntarenas · Manta · Salaverry · Callao (Lima) · Arica · Coquimbo · San Antonio · Puerto Montt · Puerto Chacabuco · Darwin Channel · Strait of Magellan · Punta Arenas · Ushuaia · Port Stanley · Montevideo · Buenos Aires
Extended 36-night voyage with 16 sea days and 21 ports. Covers Mexico, Guatemala, Costa Rica, Ecuador, and more. Includes scenic-cruising segments.
36 nights
San Diego
Patagonia & Cape Horn
21 ports
16 sea days
What this trip feels like
Long voyage with substantial time at sea
An extended voyage with 16 sea days and 21 port calls. Expect long ocean crossings and substantially more time aboard than on a typical cruise.
Broad destination variety
Cabo San Lucas · Huatulco (Santa María Huatulco) · Puerto Quetzal + more
Frequent port calls throughout the itinerary.
Route logistics
Sails from San Diego
Check the exact departure and arrival ports before arranging flights.
Port experience
Cabo San Lucas · Plan around the tender
Getting ashore usually requires tendering, and cruise traffic can add pressure to your port day.
Best for · Long-form travelers · Sea-day lovers · Multi-region exploration
Think twice if · You want a conventional one- or two-week cruise
Best departures
Best upcoming sailings
Start here. These departures surface first because they combine stronger pricing, useful timing, or a notable warning signal for this itinerary.
All departures
All upcoming departures
Compare all sailings for this itinerary.
Itinerary pricing
What this itinerary usually costs
0 of 1 sailings with enough price history currently have favorable pricing. Median current fare is $118/night.
Median current fare
$118/night
$4,249 total
Lowest recent fare
$118/night
$4,249 total
Pricing signal
0 of 1 favorable
Price history for 1 of 1 sailings
Comparison set
1 sailings
Currently priced departures
When should I go?
Not enough departures yet to identify a reliable cheaper season.
Route overview
How this route is built
36 nights · 21 port calls · 16 sea days · 9 countries
21 port calls across Mexico, Guatemala, Costa Rica, Ecuador · Typical mix of port and sea days for a 36-night cruise.
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Embark in San Diego
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Disembark in Buenos Aires
Disembarkation ports can vary by sailing
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Embark port
Disembark port
Port of call
Other routes to consider
Not quite the right itinerary? Compare routes that trade a little simplicity for more ports, different destinations, or a longer trip.
No meaningfully different nearby routes are ready to compare yet.