Port-forward pace
15 ports in 21 nights
Most days are port days.
Greek Isles cruises
Greek Isles One-Way: Cagliari, Messina & Valletta
Civitavecchia (Rome) → Cagliari → Messina → Valletta → Alexandria → Limassol → Rhodes → Heraklion → Piraeus (Athens) → Mykonos → Chania → Katakolon → Saranda → Dubrovnik → Kotor → Catania → Salerno → Civitavecchia (Rome)
Port-heavy Greek Isles itinerary. Covers Italy, Malta, Egypt, Cyprus, and more.
21 nights
Civitavecchia (Rome)
Greek Isles
15 ports
4 sea days
What this trip feels like
Port-intensive itinerary
Port-intensive itinerary with 15 port calls across 21 nights.
Broad destination variety
Cagliari · Messina · Valletta + more
Frequent port calls throughout the itinerary.
Easy logistics
Round-trip from Civitavecchia (Rome)
No open-jaw flights or separate arrival and departure transfers.
Port experience
Cagliari · Pick your date carefully
Cruise traffic varies substantially by date, so your specific port day can feel very different depending on when you visit.
Best for · Destination-led trips · Active days ashore · Travelers who prefer variety
Think twice if · You want long, uninterrupted stretches of time onboard
Best departures
Best upcoming sailings
Start here. These departures surface first because they combine stronger pricing, useful timing, or a notable warning signal for this itinerary.
All departures
All upcoming departures
Compare all sailings for this itinerary.
Itinerary pricing
What this itinerary usually costs
0 of 1 sailings with enough price history currently have favorable pricing. Median current fare is $139/night.
Median current fare
$139/night
$2,919 total
Lowest recent fare
$139/night
$2,919 total
Pricing signal
0 of 1 favorable
Price history for 1 of 1 sailings
Comparison set
1 sailings
Currently priced departures
When should I go?
Not enough departures yet to identify a reliable cheaper season.
Route overview
How this route is built
21 nights · 15 port calls · 4 sea days · 8 countries
15 port calls across Italy, Malta, Egypt, Cyprus · More port-intensive than many 21-night alternatives.
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Embark in Civitavecchia (Rome)
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Disembark in Civitavecchia (Rome)
Disembarkation ports can vary by sailing
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Port of call
Other routes to consider
Not quite the right itinerary? Compare routes that trade a little simplicity for more ports, different destinations, or a longer trip.
More port time
Add Monemvasia + Agios Nikolaos
Greek Isles: Piraeus (Athens), Monemvasia & Agios Nikolaos
22 nights · 19 ports · 3 sea days
+1 night +4 ports
Much more time ashore for only one extra night.
Compare this route →
From $26,998
Longer trip
Make it 36 nights
Western Mediterranean: Vodice, Kotor & Nafplio
36 nights · 28 ports · 8 sea days
+15 nights +4 sea days
More time at sea.
Compare this route →
From $34,503