Eastern Caribbean cruises

Eastern Caribbean Arc: Antigua, Saint Thomas & Panama Canal

Fort Lauderdale → Saint John's → Charlotte Amalie, Saint Thomas → Road Town → San Juan → Half Moon Cay → Fort Lauderdale → Half Moon Cay → Oranjestad → Cartagena → Panama Canal → Puerto Limón → Georgetown, Grand Cayman → Fort Lauderdale

Port-heavy Eastern Caribbean itinerary. Covers Antigua and Barbuda, Virgin Islands, U.S., Virgin Islands, British, Puerto Rico, and more. Includes scenic-cruising segments.

21 nights Fort Lauderdale Eastern Caribbean 15 ports 7 sea days

What this trip feels like

Port-intensive itinerary

Port-intensive itinerary with 15 port calls across 21 nights.

Port-forward pace

15 ports in 21 nights

Most days are port days.

Broad destination variety

Antigua · Saint Thomas · Tortola + more

Frequent port calls throughout the itinerary.

Easy logistics

Round-trip from Fort Lauderdale

No open-jaw flights or separate arrival and departure transfers.

Port experience

Antigua · Pick your date carefully

Cruise traffic varies substantially by date, so your specific port day can feel very different depending on when you visit.

Best for · Destination-led trips · Active days ashore · Travelers who prefer variety

Think twice if · You want long, uninterrupted stretches of time onboard

Best departures

Best upcoming sailings

Start here. These departures surface first because they combine stronger pricing, useful timing, or a notable warning signal for this itinerary.

All departures

All upcoming departures

Compare all sailings for this itinerary.

Itinerary pricing

What this itinerary usually costs

0 of 2 sailings with enough price history currently have favorable pricing. Median current fare is $124/night.

Median current fare

$124/night

$2,597 total

Lowest recent fare

$122/night

$2,554 total

Pricing signal

0 of 2 favorable

Price history for 2 of 2 sailings

Comparison set

2 sailings

Currently priced departures

When should I go?

Not enough departures yet to identify a reliable cheaper season.

Route overview

How this route is built

Compare sailings →

21 nights · 15 port calls · 7 sea days · 11 countries

15 port calls across Antigua and Barbuda, Virgin Islands, U.S., Virgin Islands, British, Puerto Rico · More port-intensive than many 21-night alternatives.

  1. 1

    Embark in Fort Lauderdale

    Embarkation ports can vary by sailing

  2. 2

    Antigua

    Antigua and Barbuda · Eastern Caribbean

  3. 3

    Saint Thomas

    Virgin Islands, U.S. · Eastern Caribbean

  4. 4

    Tortola

    Virgin Islands, British · Eastern Caribbean

  5. 5

    San Juan

    Puerto Rico · Eastern Caribbean

  6. 6

    Half Moon Cay

    Bahamas · Bahamas

  7. 7

    Fort Lauderdale

    United States · US East Coast

  8. 8

    Half Moon Cay

    Bahamas · Bahamas

  9. 9

    Oranjestad

    Aruba · ABC Islands

  10. 10

    Cartagena

    Colombia · Southern Caribbean

  11. 11

    Panama Canal

    Panama · Panama Canal

    Scenic cruising
  12. 12

    Panama Canal

    Panama · Panama Canal

    Scenic cruising
  13. 13

    Panama Canal

    Panama · Panama Canal

    Scenic cruising
  14. 14

    Colón (Panama Canal)

    Panama · Panama Canal

  15. 15

    Puerto Limón

    Costa Rica · Central America

  16. 16

    Georgetown, Grand Cayman

    Cayman Islands · Western Caribbean

  17. 17

    Disembark in Fort Lauderdale

    Disembarkation ports can vary by sailing

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Embark port
Disembark port
Port of call

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