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Central America cruises

Central America One-Way via Cabo San Lucas, Puerto Quetzal & Panama Canal

Cabo San Lucas · Acapulco · Puerto Quetzal · Acajutla · Puntarenas · Panama Canal · Cartagena

Balanced route with a steady mix of port days and sea days. Covers Mexico, Guatemala, El Salvador, Costa Rica, and more. Includes scenic-cruising segments.

17 nights San Diego Central America 7 ports 10 sea days
Compare departures Explore the route

What this trip feels like

Balanced, varied and easy to pace

This route gives you a steady mix of ship time and 7 ports. It suits travelers who want meaningful days ashore without turning every day into an early start and a tightly planned port call.

Balanced pace

7 ports in 17 nights

A steady alternation between time onboard and time ashore.

Broad destination variety

Cabo San Lucas · Acapulco · Puerto Quetzal + more

Frequent changes of scenery across the itinerary.

Route logistics

Sails from San Diego

Check the exact departure and arrival ports before arranging flights.

Port experience

Cabo San Lucas · Plan around the tender

Getting ashore usually requires tendering, and cruise traffic can add pressure to your port day.

Best for · A mix of ship and shore time · First-time visitors · Travelers who like a steady pace

Think twice if · You want either an all-ports itinerary or a mostly ship-focused escape

Best departures

Best upcoming sailings

Start here. These departures surface first because they combine stronger pricing, useful timing, or a notable warning signal for this itinerary.

Best overall value
Azamara Cruises

Azamara Quest

San Diego → Cabo San Lucas → Cartagena → Miami

May 24 · 17 nights

$6,219 inside · $366/night

All departures

All upcoming departures

Compare all sailings for this itinerary.

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Itinerary pricing

What this itinerary usually costs

Typical pricing runs around $351/night, with most departures landing in the $312-$354/night band across 1 tracked sailing.

Typical price

$351/night

$5,959 total

Normal range

$312-$354/night

$5,309-$6,019 total

Lowest recent fare

$366/night

$6,219 total

Comparison set

1 sailings

Used for itinerary baseline

When should I go?

Not enough departures yet to identify a reliable cheaper season.

Route overview

How this route is built

Compare sailings →

17 nights · 7 port calls · 10 sea days · 6 countries

7 port calls across Mexico, Guatemala, El Salvador, Costa Rica · Neither especially port-heavy nor sea-day heavy for this trip length.

  1. 1

    Embark in San Diego

    Embarkation ports can vary by sailing

  2. 2

    Cabo San Lucas

    Mexico · Mexican Riviera

  3. 3

    Acapulco

    Mexico · Mexican Riviera

  4. 4

    Puerto Quetzal

    Guatemala · Central America

  5. 5

    Acajutla

    El Salvador · Central America

  6. 6

    Puntarenas

    Costa Rica · Central America

  7. 7

    Panama Canal

    Panama · Panama Canal

    Scenic cruising
  8. 8

    Cartagena

    Colombia · Southern Caribbean

  9. 9

    Disembark in Miami

    Disembarkation ports can vary by sailing

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Embark port
Disembark port
Port of call

Other routes to consider

Not quite the right itinerary? Compare routes that trade a little simplicity for more ports, different destinations, or a longer trip.

FAQ

What’s the best month to sail this itinerary?
It depends on weather and crowd levels. Use the sailing list to compare dates and prioritize port days with comfortable conditions.
Are these sailings all the same route?
They can be close but not identical. Look for differences in port order, arrival times, and sea day placement.
How should I choose between two similar sailings?
Compare: (1) ship, (2) port day timing, (3) number of sea days, (4) price vs cabin value, and (5) flight convenience.