Port-forward pace
16 ports in 21 nights
Most days are port days.
Adriatic Sea cruises
Adriatic Sea Circuit: Santorini, Chania & Messina
Piraeus (Athens) → Santorini → Chania → Katakolon → Messina → Valletta → Dubrovnik → Kotor → Split → Trieste → Bar → Kotor → Corfu (Kérkira) → Valletta → Messina → Naples → Civitavecchia (Rome)
Port-heavy Adriatic Sea itinerary. Covers Greece, Italy, Malta, Croatia, and more.
21 nights
Piraeus (Athens)
Adriatic Sea
16 ports
4 sea days
What this trip feels like
Port-intensive itinerary
Port-intensive itinerary with 16 port calls across 21 nights.
Broad destination variety
Santorini · Chania · Katakolon + more
Frequent port calls throughout the itinerary.
Route logistics
Sails from Piraeus (Athens)
Check the exact departure and arrival ports before arranging flights.
Port experience
Santorini · Plan around the tender
Getting ashore usually requires tendering, and cruise traffic can add pressure to your port day.
Best for · Destination-led trips · Active days ashore · Travelers who prefer variety
Think twice if · You want long, uninterrupted stretches of time onboard
Best departures
Best upcoming sailings
Start here. These departures surface first because they combine stronger pricing, useful timing, or a notable warning signal for this itinerary.
All departures
All upcoming departures
Compare all sailings for this itinerary.
Itinerary pricing
What this itinerary usually costs
0 of 1 sailings with enough price history currently have favorable pricing. Median current fare is $154/night.
Median current fare
$154/night
$3,238 total
Lowest recent fare
$154/night
$3,238 total
Pricing signal
0 of 1 favorable
Price history for 1 of 1 sailings
Comparison set
1 sailings
Currently priced departures
When should I go?
Not enough departures yet to identify a reliable cheaper season.
Route overview
How this route is built
21 nights · 16 port calls · 4 sea days · 5 countries
16 port calls across Greece, Italy, Malta, Croatia · More port-intensive than many 21-night alternatives.
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Embark in Piraeus (Athens)
Embarkation ports can vary by sailing
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Disembark in Civitavecchia (Rome)
Disembarkation ports can vary by sailing
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Embark port
Disembark port
Port of call
Other routes to consider
Not quite the right itinerary? Compare routes that trade a little simplicity for more ports, different destinations, or a longer trip.
More port time
Add Gytheio + Itea
Adriatic Sea: Piraeus (Athens), Gytheio & Itea
21 nights · 19 ports · 2 sea days
Same length +3 ports
Much more time ashore without making the trip longer.
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More variety
Add Porto Santo Stefano + Salerno
Adriatic Sea: Porto Santo Stefano, Salerno & Giardini Naxos
28 nights · 23 ports · 7 countries
+7 nights +2 countries
A much broader Adriatic Sea experience.
Compare this route →
From $21,798